NEET PG DENTAL EXAM

HISTOLOGY

INTEGUMENTARY SYSTEM SKIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The basale layer which includes dividing keratinocytes that act as stem cells are located where in the skin?
A
bottom of the dermis
B
bottom of the hypodermis
C
bottom of the epidermis
D
none of these
Explanation: 

Detailed explanation-1: -The basal layer is the innermost layer of the epidermis, and contains small round cells called basal cells. The basal cells continually divide, and new cells constantly push older ones up toward the surface of the skin, where they are eventually shed.

Detailed explanation-2: -Merkel cells are oval-shaped modified epidermal cells found in stratum basale, directly above the basement membrane. These cells serve a sensory function as mechanoreceptors for light touch, and are most populous in fingertips, though also found in the palms, soles, oral, and genital mucosa.

Detailed explanation-3: -The epidermal stem cells lie in the basal layer, attached to the basal lamina. Progeny that become committed to differentiation go through several rapid divisions in the basal layer, and then stop dividing and move out toward the surface of the skin.

Detailed explanation-4: -The stratum basale is a single layer of cells primarily made of basal cells. A basal cell is a cuboidal-shaped stem cell that is a precursor of the keratinocytes of the epidermis. All of the keratinocytes are produced from this single layer of cells, which are constantly going through mitosis to produce new cells.

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