HISTOLOGY
INTEGUMENTARY SYSTEM SKIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Langerhans cells
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Stratum Corneum
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Pronarinhan cells
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Ligamental cells
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Detailed explanation-1: -Langerhans cells are dendritic cells in the epidermis that have an immunologic function (Fig. 2.4). They are derived from the bone marrow and constitute about 5% of the cells within the epidermis. On electron microscopic examination, characteristic “tennis racket”-shaped granules are seen.
Detailed explanation-2: -The Langerhans cell is a dendritic cell meaning it is an antigen presenting cell – able to latch onto, process and present antigens to T cells on its cell surface. They can be found as star shaped cells within all areas of the epidermis and histologically they contain dark-staining spots known as Birbeck granules.
Detailed explanation-3: -Dendritic cells (DCs)3 are professional APCs that play a crucial role in activating adaptive immune responses. Langerhans cells (LCs) are a subset of immature DCs that reside in the epidermis. LCs are distinguished from other DCs by the presence of cytoplasmic organelles, known as Birbeck granules (1).