HISTOLOGY
INTEGUMENTARY SYSTEM SKIN
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Keratinocytes
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Langerhans cells
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Melanocytes
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Merkel cells
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Detailed explanation-1: -Merkel cells are in the layer of basal cells at the deepest part of the epidermis and are connected to nerves.
Detailed explanation-2: -Merkel cells are found in the epidermis. Merkel cells normally exist in the bottom (basal) layer of the epidermis, about 0.1 mm from skin’s surface. (outer layer of the skin). They were originally described in the late 1800s by Friedrich Merkel, a German anatomist.
Detailed explanation-3: -Merkel cells are epithelial neuroendocrine cells. Although their origin is unclear, they are thought to arise from epidermal ectoderm rather than neural crest. Merkel cells are rare and are found in the basal layer of the epidermis and around the bulge region of hair follicles.
Detailed explanation-4: -Merkel cells function as type 1 mechano-receptors and can sense light touches. They are part of the tactile-end organs in the skin, which include Merkel discs, Pacinian corpuscles, Meissner’s corpuscles, and Ruffini endings [30].