HISTOLOGY
NERVOUS TISSUE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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more negative on the inside compared to the outside
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more positive on the inside compared to the outside
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equal charge distribution inside and outside the cell
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None of the above
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Detailed explanation-1: -The resting membrane potential of a neuron is about-70 mV (mV=millivolt)-this means that the inside of the neuron is 70 mV less than the outside. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron.
Detailed explanation-2: -The inside of the neuron is more negatively charged than the outside. Figure 4.1. For a typical neuron at rest, sodium, chloride, and calcium are concentrated outside the cell, whereas potassium and other anions are concentrated inside. This ion distribution leads to a negative resting membrane potential.
Detailed explanation-3: -Neurons actually have a pretty strong negative charge inside them, in contrast to a positive charge outside. This is due to other molecules called anions. They are negatively charged, but are way too big to leave through any channel. They stay put and give the cell a negative charge inside.