NEET PG DENTAL EXAM

HISTOLOGY

URINARY SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
____ are specialized epithelial cells of the distal convoluted tubule. These cells sense sodium chloride concentration in the tubule, which in turn reflects the systemic blood pressure.
A
Podocytes
B
Juxtaglomerular cells
C
Mesangial cells
D
Macula densa
Explanation: 

Detailed explanation-1: -The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule.

Detailed explanation-2: -In the adjacent distal convoluted tubule, specialized cells, called macula densa, act as chemoreceptors that monitor the concentration of Na + and Cl – in the urine inside the tubule. Together, these cells help regulate blood pressure and the production of urine in the nephron.

Detailed explanation-3: -Macula densa cells in the distal nephron, according to the classic paradigm, are salt sensors that generate paracrine chemical signals in the juxtaglomerular apparatus to control vital kidney functions, including renal blood flow, glomerular filtration, and renin release.

Detailed explanation-4: -Macula densa is a type of cell that is located in the cell lining of the distal convoluted tubule (DCT). It helps in regulating important renal processes such glomerular filtration rate, renal blood flow, and renin release. The salt content (NaCl) in DCT, affects these cells.

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