HISTOLOGY
URINARY SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the role of podocytes in the nephron?
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Allow for filtration according to size
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Allow for filtration according to pH
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Secretion
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Excretion
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Explanation:
Detailed explanation-1: -Podocytes are also involved in regulation of glomerular filtration rate (GFR). When podocytes contract, they cause closure of filtration slits. This decreases the GFR by reducing the surface area available for filtration.
Detailed explanation-2: -The glomerular filtration barrier selectively filters molecules based on size (70 kDa), electrical charge (the more cationic, the more permeable), and capillary pressure.
Detailed explanation-3: -The glomerular filtration barrier is a highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules.
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