NEET PG DENTAL EXAM

Detailed explanation-1: -Most of the glucose entering the tubular system is reabsorbed along the nephron segments, primarily in the proximal tubule, such that urine is almost free of glucose. This is different in diabetes, where the filtered glucose exceeds the transport capacity of the tubular system for glucose and glucosuria occurs.

Detailed explanation-2: -Tubular reabsorption occurs when the kidneys reabsorb useful substances, such as glucose, amino acids, and electrolytes, from the filtrate back into the bloodstream. This process occurs primarily in the proximal tubule of the nephron and is critical in maintaining the body’s electrolyte and fluid balance.

Detailed explanation-3: -The kidneys reabsorb filtered glucose through the sodium‐glucose cotransporters sodium‐glucose cotransporter (SGLT) 1 and SGLT2, which are localized on the brush border membrane of the early proximal tubule with immune detection of their expression in the tubularized Bowman capsule.