PSYCHOLOGY OF EMOTIONS

THE PSYCHOLOGY OF EMOTIONS

STATES OF CONSCIOUSNESS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cocaine blocks the reuptake of which neurotransmitters?
A
Epinephrine
B
Endorphins
C
GABA
D
Substance P
E
Dopamine
Explanation: 

Detailed explanation-1: -Cocaine inhibits the re-uptake of synaptic dopamine and serotonin, as well as norepinephrine by binding with high affinity to the serotonin transporter (SERT), dopamine transporter (DAT) and norepinephrine transporter (NET).

Detailed explanation-2: -For example, cocaine acts by binding to the dopamine transporter, blocking the removal of dopamine from the synapse.

Detailed explanation-3: -Dopamine antagonist drugs include: chlorpromazine (Thorazine) metoclopramide (Reglan) promethazine (Phenergan)

Detailed explanation-4: -Cocaine increases dopamine levels by inhibiting reuptake through the dopaminergic transporter. However, this mechanism is insufficient to account for all of the actions of cocaine on the dopaminergic system.

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