PSYCHOLOGY OF EMOTIONS

Detailed explanation-1: -Tolerance. The more often a drug is used, the more the brain becomes used to its effects, and the more established its pattern of homeostatic responses to the drug’s presence becomes. This is called neuroadaptation. A common effect of this is a young person’s increased tolerance to the drug.

Detailed explanation-2: -Neuroadaptation refers largely to the processes by which initial drug effects are either enhanced (i.e., sensitization) or attenuated (i.e., counteradaptation) by repeated AOD exposure. Drug-related responses (i.e., reinforcement) are modulated by the neuroadaptive changes that occur with AOD exposure.

Detailed explanation-3: -In the context of the study of drugs, tolerance refers to the decreased effectiveness of a given drug with repeated administration; sensitization to the increased effectiveness with repeated administration.

Detailed explanation-4: -Sensitization, also referred to as reverse tolerance, is a phenomenon in which following repeated exposure to the same dose of a particular drug of abuse, a specific behavioral, physiological, or cellular response increases, rather than decreases, over time. Such sensitized responses can persist for weeks or months.