PSYCHOLOGY OF EMOTIONS

Detailed explanation-1: -Generally, tolerance leads to increasing doses of a drug being required to produce the same effect. Other possible mechanisms are a decrease in binding affinity between a drug and receptor and a decrease in the number of receptors.

Detailed explanation-2: -If your body has developed a tolerance to a medication you’re taking, it means the medication at your current dose has stopped working as effectively as it once did. It might mean your body becomes used to the medication, and you don’t get the same benefits or effects as before.