THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Background: Hirschsprung disease is one of the most common congenital anomalies that affect colorectal function. Rectal biopsy demonstrating the absence of ganglion cells in the affected bowel is the gold standard for diagnosis.

Detailed explanation-2: -Doctors typically use rectal biopsies to confirm or rule out a diagnosis of Hirschsprung disease. During a rectal biopsy procedure, a doctor will take small pieces of tissue from the rectum. A pathologist will examine the tissue under a microscope to look for signs of Hirschsprung disease.

Detailed explanation-3: -Rectal Suction Biopsy (RSB) Data and Efficacy. The median number of RSB specimens per patient sent to the pathologists was three (range one to five). The diagnostic efficacy, defined as sufficient specimens to determine the presence or absence of ganglion cells, of first-time RSB was 85% (71/84) (Table 1).

Detailed explanation-4: -A rectal biopsy is used to determine the cause of abnormal growths found during anoscopy, sigmoidoscopy, or other tests. It can also be used to confirm the diagnosis of amyloidosis (rare disorder in which abnormal proteins build up in tissues and organs).