MEDICAL
KIDNEY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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thin layer-short diffusion distance
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microvilli-large surface area
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partially permeable
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None of the above
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Detailed explanation-1: -The proximal convoluted tubule is lined by a simple cuboidal epithelium with a brush border of microvilli, which greatly increase the surface area of the inner lining of the tubule in order to maximize the number of active and passive transport proteins in the lining cell membranes.
Detailed explanation-2: -Epithelial cells in the proximal convoluted tubule (PCT) reabsorb components of the glomerular filtrate that have nutritional significance (e.g., glucose, ions and amino acids). To facilitate absorption, these cells have numerous microvilli, Mv, along their apical surface.
Detailed explanation-3: -The proximal convoluted tubule (PCT) uses both cellular and paracellular transport mechanisms. The apical membrane has an expanded surface area available for reabsorption and tight junctions enabling high-capacity fluid reabsorption.