THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -There are four major hereditary renal cell carcinoma (RCC) syndromes. These syndromes are summarized in detail in the following PDQ summaries and in Table 1 below: Von Hippel-Lindau Disease (VHL). Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC). Hereditary Papillary Renal Carcinoma (HPRC).

Detailed explanation-2: -More than 55% of von Hippel-Lindau disease (VHL)-affected individuals only develop multiple renal cell cysts. The VHL-associated renal cell carcinomas (RCCs) that occur are characteristically multifocal and bilateral; these RCCs present as combined cystic and solid masses.

Detailed explanation-3: -People with von Hippel-Lindau syndrome commonly develop cysts in the kidneys, pancreas, and genital tract. They are also at an increased risk of developing a type of kidney cancer called clear cell renal cell carcinoma and a type of pancreatic cancer called a pancreatic neuroendocrine tumor.