MEDICAL
KIDNEY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Ions like Na+ and Cl-
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Nutrients like glucose and amino acids
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Substances like drug metabolites and waste
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Water
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Detailed explanation-1: -Final answer: Proximal convoluted tubule is involved in reabsorption of water even in presence of hormone ADH (Anti-diuretic hormone).
Detailed explanation-2: -Water reabsorption across many “tight” urinary epithelia is driven by large transepithelial osmotic gradients and is controlled by antidiuretic hormone (ADH). Numerous investigators have concluded that ADH-induced water reabsorption causes large apparent increases in cell volume with concomitant cytoplasmic dilution.
Detailed explanation-3: -After entering the duct cell from the collecting duct lumen through the AQP2 channels, the water exits the cell through the AQP3 and AQP4 channels located in the cell basolateral membrane, causing the water to enter the interstitial space of the nephron.