THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Polycystic kidney disease (PKD) is an inherited disorder in which clusters of cysts develop primarily within your kidneys, causing your kidneys to enlarge and lose function over time. Cysts are noncancerous round sacs containing fluid. The cysts vary in size, and they can grow very large.

Detailed explanation-2: -Polycystic kidney disease Mutations in the PKD1 gene include deletions or insertions of DNA building blocks (base pairs) and alterations of one or more base pairs. Most PKD1 mutations are predicted to produce an abnormally small, nonfunctional version of the polycystin-1 protein.

Detailed explanation-3: -In a few cases, PCOS has been reported in female PKD patients [80]. However, it is suggested that PKD patients and their unaffected relatives do not exhibit elevated risks of PCOS. This study includes a broad spectrum of female PKD patients, including premenopausal and postmenopausal female PKD patients.

Detailed explanation-4: -Polycystic kidney disease (also called PKD) causes numerous cysts to grow in the kidneys. These cysts are filled with fluid. If too many cysts grow or if they get too big, the kidneys can become damaged. PKD cysts can slowly replace much of the kidneys, reducing kidney function and leading to kidney failure.