THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -One way of thinking of this is that it is very much like the National Lottery. That is, we all have our own six numbers and if the donor had the same six numbers as one of the recipients on the list, they would be offered that kidney. This is called a ‘6-antigen match’ or a ‘full house match’.

Detailed explanation-2: -HLA typing is a crucial step in renal transplantation, as recognition of foreign HLA by recipient T lymphocytes would trigger an immune response. T lymphocyte activation initiates a cascade of mediators that direct the immune system against the allograft[8].

Detailed explanation-3: -HLA class I and II matching is important in organ transplantation [3] especially in kidney and bone marrow transplantation. In heart and lung transplantation, HLA match at the DR locus is important but there is some difficulties like ischemic times, availability of donors and clinical need of recipients.