MEDICAL
KIDNEY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which portion of the nephron active pumps out Na+, with Cl-passively following, to create a salty medulla?
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Proximal convoluted tubule
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Ascending loop of Henle
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Distal convoluted tubule
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Both proximal convoluted tubule and ascending loop of Henle
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Explanation:
Detailed explanation-1: -As discussed above, the ascending loop has many Na+ pumps that actively pump Na+ out of the forming urine into the interstitial spaces. In addition, collecting ducts have urea pumps that actively pump urea into the interstitial spaces.
Detailed explanation-2: -The ascending limb (where loop diuretics work) is impermeable to water. NaCl is pumped from the tubule into the interstitium in the ascending limb.
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