MEDICAL
KIDNEY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It is too large to be filtered through the Bowman’s capsule
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It is rebsorbed in the collecting duct
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It is rebsorbed in the distal convoluted tubule
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It is rebsorbed in the proximal convoluted tubule
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Detailed explanation-1: -Further, if excreted in the urine, glucose will “drag” valuable ions (e.g., Na+ and K+) and water during an osmotic diuresis. Therefore, glucose is not excreted in the urine unless its filtered load exceeds the tubular maximum capacity for its reabsorption.
Detailed explanation-2: -The amount of glucose reabsorbed by the proximal tubule is determined by the body’s need to maintain a sufficient level of glucose in the blood. If the concentration of blood glucose becomes too high (160-180 mg/dL), the tubules no longer reabsorb glucose, allowing it to pass through into the urine.
Detailed explanation-3: -Under normal circumstances, up to 180 g/day of glucose is filtered by the renal glomerulus and virtually all of it is subsequently reabsorbed in the proximal convoluted tubule. This reabsorption is effected by two sodium-dependent glucose cotransporter (SGLT) proteins.
Detailed explanation-4: -This is associated with diabetes mellitus. Firstly, the glucose in the proximal tubule is co-transported with sodium ions into the proximal convoluted tubule walls via the SGLT2 cotransporter.