MEDICAL
LIVER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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it will produce insulin and convert glucose to glycogen
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it will produce glucagon and convert glycogen to glucose
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it will convert glucose to glycogen and store this in hepatocytes
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it will convert glycogen to glucose and release this into the blood
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Detailed explanation-1: -This excess glucose is dealt with by glycogenesis in which the liver converts glucose into glycogen for storage. The glucose that is not stored is used to produce energy by a process called glycolysis. This occurs in every cell in the body. In between meals or during starvation, blood glucose levels fall.
Detailed explanation-2: -In the fed state, glucose enters hepatocytes via GLUT2 and is phosphorylated by glucokinase and used to synthesize glycogen by glycogen synthase (4). In the fasted state, glycogen is hydrolyzed by glycogen phosphorylase to generate glucose (glycogenolysis) (Fig. 1).
Detailed explanation-3: -Glycogen is mainly stored in the liver (where it makes up as much as 10% of liver weight and can be released back into the blood stream) and muscle (where it can be converted back to glucose but only used by the muscle). Therefore, excess glucose is removed from the blood stream and stored.