THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Kupffer cells are resident liver macrophages and play a critical role in maintaining liver functions. Under physiological conditions, they are the first innate immune cells and protect the liver from bacterial infections.

Detailed explanation-2: -Kupffer cells are macrophages that are fixed within the sinusoids of the liver. They are the body’s most abundant source of fixed macrophages.

Detailed explanation-3: -Hepatic macrophages, consisting of liver resident Kupffer cells (KCs) and monocyte-derived macrophages (MoMs), play a central role in maintaining homeostasis of the liver as well as contributing to the progression of acute or chronic liver injury (1).

Detailed explanation-4: -Macrophages represent by far the most abundant immune cells in the liver. Hepatic macrophages are still often referred as Kupffer cells (KCs) that indeed represent the major fraction of liver macrophages.