THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Specialized peripheral sensory neurons known as nociceptors alert us to potentially damaging stimuli at the skin by detecting extremes in temperature and pressure and injury-related chemicals, and transducing these stimuli into long-ranging electrical signals that are relayed to higher brain centers.

Detailed explanation-2: -Nociceptors respond to certain temperature range and mechanical stimulus. The peripheral end of the axon contains encapsulated proteins called transduction proteins (TRP), which can be activated by a specic stimulus.

Detailed explanation-3: -Three types of stimuli can activate pain receptors in peripheral tissues: mechanical (pressure, pinch), heat, and chemical. Mechanical and heat stimuli are usually brief, whereas chemical stimuli are usually long lasting.