MEDICAL
PANCREAS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A 40-year-old woman presents with an 8-month historyof generalized itching, weight loss, fatigue, and yellowsclerae. Physical examination reveals mild jaundice. Aliver biopsy discloses bile duct injury and inflammation.Which of the following cells forms the lining epitheliumof the biliary tree?
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Cholangiocytes
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Endothelial cells
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Hepatic stellate cells
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Hepatocytes
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Kupffer cells
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Explanation:
Detailed explanation-1: -Obstructive jaundice is a specific type of jaundice, where symptoms develop due to a narrowed or blocked bile duct or pancreatic duct, preventing the normal drainage of bile from the bloodstream into the intestines.
Detailed explanation-2: -Cholangiocytes are a heterogeneous, highly dynamic population of epithelial cells that line a three-dimensional network of bile ducts known as the biliary tree. Their major physiologic function lies in modification of hepatic canalicular (i.e., primary) bile as it is transported along the biliary tree.
Detailed explanation-3: -The normal ratio of bile ducts to portal tracts is between 0.9 and 1.8; a ratio of less than 0.4 clearly confirms a reduction in bile ducts.
There is 1 question to complete.