THORAX ABDOMEN AND PELVIS

MEDICAL

PANCREAS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Trypsinogen is converted into its active form, trypsin, by
A
cholecystokinin
B
secretin
C
enterokinase
D
lipase
Explanation: 

Detailed explanation-1: -Mold kinase transforms trypsinogen to trypsin only in an acid medium. It differs thus from enterokinase and trypsin which activate trypsinogen best in a slightly alkaline medium.

Detailed explanation-2: -Once trypsinogen is released into the lumen of the small intestine, enterokinase produced by the duodenal mucosa converts trypsinogen into an active form, trypsin.

Detailed explanation-3: -Enterokinase is a protease of the intestinal brush border that specifically cleaves the acidic propeptide from trypsinogen to yield active trypsin. This cleavage initiates a cascade of proteolytic reactions leading to the activation of many pancreatic zymogens.

There is 1 question to complete.