THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Each lobule is made up of numerous liver cells, called hepatocytes, that line up in radiating rows. Between each row are sinusoids.

Detailed explanation-2: -Four major liver cell types-hepatocytes (HCs), hepatic stellate cells (HSCs), Kupffer cells (KCs), and liver sinusoidal endothelial cells (LSECs)-spatiotemporally cooperate to shape and maintain liver functions.

Detailed explanation-3: -The hepatic lobule is the anatomic unit of the liver. In the anatomic model, liver lobules are organized into irregular polygons demarcated by connective tissue and composed of plates of hepatocytes radiating outward from the central vein to the portal triads (Figure 61-1).