THORAX ABDOMEN AND PELVIS

MEDICAL

RECTUM AND ANUS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
____ stimulates parietal, chief, and ECL cells.
A
Gastrin
B
Secretin
C
Histamine
D
Somatostatin
Explanation: 

Detailed explanation-1: -Gastrin stimulates proliferation and the differentiation of parietal and ECL cells; it also stimulates acid secretion from parietal cells, at least in part by increasing histamine synthesis and release in ECL cells.

Detailed explanation-2: -Gastrin is a potent stimulus of gastric acid secretion by stimulating the release of histamine from ECL cells[12-16]. The gastrin-ECL cell axis plays a critical role in regulating acid secretion from parietal cells.

Detailed explanation-3: -The cells are stimulated by gastrin and pituitary adenylate cyclase activating peptide and suppressed by somatostatin and galanin. Choline esters and histamine seem to be without effect on ECL cell secretion.

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