THORAX ABDOMEN AND PELVIS

MEDICAL

RECTUM AND ANUS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Regarding pepsinogen secretion:
A
It is required for fat digestion
B
Secreted by the pyloric gland
C
Convert in its active form only in acidity environment
D
Secreted by enterochromaffin-like cells (ECL)
Explanation: 

Detailed explanation-1: -Pepsin is an aspartic protease that acts in food digestion in the mammal stomach. An optimal pH of around 2 allows pepsin to operate in its natural acidic environment, while at neutral pH the protein is denatured.

Detailed explanation-2: -HCl is one of the constituents of gastric juice, which is secreted by the stomach. HCl provides the acidic pH to convert pepsinogen (inactive) into pepsin (active). Pepsin digests proteins by breaking them down into proteoses and peptones. HCl also helps to destroy bacteria as well as other harmful microorganisms.

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