THORAX ABDOMEN AND PELVIS

MEDICAL

SPLEEN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Splenectomy results in the following changes in the peripheral blood film EXCEPT
A
target cells
B
Howell jolly bodies
C
reticulocytosis
D
Basophilic stippling
Explanation: 

Detailed explanation-1: -Basophilic stippling is a frequent manifestation of hematologic disease in the peripheral blood, and it is also observable in bone marrow aspirates. It is implicated in cases of lead poisoning but can be an indicator of various heavy metal toxicities.

Detailed explanation-2: -Hematopathology. The nucleated RBCs contain basophilic stippling of the cytoplasm. This suggests a toxic injury to the bone marrow, such as lead poisoning. Such stippling may also appear with severe anemia, such as a megaloblastic anemia.

Detailed explanation-3: -An increase in blood leukocytes can occur following a splenectomy. The post-splenectomy platelet count may rise to abnormally high levels (thrombocytosis), leading to an increased risk of potentially fatal clot formation.

There is 1 question to complete.