THORAX ABDOMEN AND PELVIS

MEDICAL

SPLEEN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The following statements are TRUE regarding spleen, EXCEPT
A
The red pulp of the spleen is highly vascular.
B
White pulp of the spleen is composed of lymphoid aggregates.
C
lymphoid nodules in the white pulp is composed mainly of B-lymphocytes
D
periarteriolar lymphoid sheath is composed mainly of B-lymphocytes
Explanation: 

Detailed explanation-1: -The T-cell zone is represented by the periarteriolar lymphoid sheath, primarily consisting of tightly packed lymphocytes and the presence of interdigitating dendritic cells.

Detailed explanation-2: -The two major functional zones of the spleen are the hematogenous red pulp and the lymphoid white pulp. The white pulp, located around a central arteriole, is composed of the periarteriolar lymphoid sheath (PALS, T-cell area), the adjacent follicles (B-cell area), and marginal zone (B-cell area) (Figure 1).

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