THORAX ABDOMEN AND PELVIS

MEDICAL

STOMACH

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Pepsinogen, the precursor to pepsin, is secreted by
A
chief cells
B
G-cells
C
parietal cells
D
mucous cells
Explanation: 

Detailed explanation-1: -Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.

Detailed explanation-2: -Structure. The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40, 400. Pepsin, an enzyme with a molecular weight of 32, 700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.

Detailed explanation-3: -Pepsinogen is a precursor molecule that is converted into the enzyme pepsin in the highly acidic environment of the stomach. Pepsin breaks down proteins in food into smaller polypeptides that can further be broken down into single amino acids in the intestine.

There is 1 question to complete.