THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -Parietal cells contain an extensive secretory network (called canaliculi) from which the “hydrochloric acid” is secreted into the lumen of the stomach. The pH of gastric acid is 1.5 to 3.5 in the human stomach lumen, a level maintained by the proton pump H+/K+ ATPase.

Detailed explanation-2: -When stimulated, parietal cells secrete HCl at a concentration of roughly 160 mM (equivalent to a pH of 0.8). The acid is secreted into large cannaliculi, deep invaginations of the plasma membrane which are continuous with the lumen of the stomach.

Detailed explanation-3: -The gastric mucosa is present is in the inner wall of the stomach which secretes 1.2 to 1.5 litres of gastric juice per day.

Detailed explanation-4: -Basic Mechanism of Hydrochloric Acid Secretion. Whenstimulated, the parietal cells secrete an acid solution that contains about 160 millimoles of hydrochloric acid per liter, which is almost exactly isotonic with the body fluids. The pH of this acid is about 0.8, demonstrating its extreme acidity.