MEDICAL
STOMACH
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The gall bladder
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The stomach
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The pancreas
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The mouth
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Detailed explanation-1: -Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.
Detailed explanation-2: -Pepsinogen is secreted from peptic (or chief) cells in the oxyntic gland. Some pepsinogen is also secreted from mucosal cells in the gastric antrum and the duodenum. In the presence of gastric acid this proenzyme is converted into active pepsin, which itself catalyzes further conversion from pepsinogen.
Detailed explanation-3: -Pepsinogens are converted in the gastric lumen by gastric acid to pepsins, which contain two active-site aspartate residues. Once this reaction begins, pepsins can autocatalyze the conversion of pepsinogens to pepsins.