THORAX ABDOMEN AND PELVIS

Detailed explanation-1: -These studies suggest that: (a) Both secretin and cholecystokinin augment pyloric sphincter pressure while gastrin I is an antagonist inhibiting their effects.

Detailed explanation-2: -As two of the first gastrointestinal peptides discovered, gastrin and CCK are known to play important roles in digestive processes including gastric acid secretion, pancreatic enzyme release, gallbladder emptying, gut motility, and energy homeostasis (2–4).

Detailed explanation-3: -The main effect of secretin is to stimulate pancreatic secretion, especially pancreatic ducts. It increases the secretion of HCO 3-, water and ions, and thus the secretion of aqueous alkaline pancreatic juice. It reduces the secretion of gastric juice and can cause a contraction of the pyloric sphincter.