ANATOMY

Detailed explanation-1: -Macrophages are effector cells of the innate immune system that phagocytose bacteria and secrete both pro-inflammatory and antimicrobial mediators. In addition, macrophages play an important role in eliminating diseased and damaged cells through their programmed cell death.

Detailed explanation-2: -Macrophages and neutrophils (phagocytes) are the front-line defenders in your body’s immune system. They seek out, ingest, and destroy pathogens and other debris through a process called phagocytosis.

Detailed explanation-3: -A type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Detailed explanation-4: -Macrophages are scavengers whose job is to engulf or eat up infecting germs and even infected cells. Macrophages also help to overcome infection by secreting signals that help activate other cell types to fight against infections.

Detailed explanation-5: -Once engulfed, cellular enzymes inside the macrophage destroy the ingested particle. Some macrophages act as scavengers, removing dead or necrotic cells while others provide host immunity by engulfing microbes.