ANATOMY

Detailed explanation-1: -The spleen is a small organ inside your left rib cage, just above the stomach. It’s part of the lymphatic system (which is part of the immune system). The spleen stores and filters blood and makes white blood cells that protect you from infection. Many diseases and conditions can affect how the spleen works.

Detailed explanation-2: -Organs and tissues important to the proper functioning of the immune system include the thymus and bone marrow, lymph nodes and vessels, spleen, and skin.

Detailed explanation-3: -The spleen is a reservoir of different immune cells, some with anti-tumor immunity like T cells, B cells, NK cells, and macrophages.

Detailed explanation-4: -The physical organization of the spleen allows it to filter blood of pathogens and abnormal cells and facilitate low probability interactions between antigen presenting cells (APCs) and cognate lymphocytes. APCs unique to the spleen regulate the T and B cell response to these antigenic targets in the blood.

Detailed explanation-5: -Bone marrow. Bone marrow is a sponge-like tissue found inside the bones. Thymus. The thymus is located behind the breastbone above the heart. Lymph nodes. Spleen. Tonsils. Mucous membranes. 30-Jul-2020