ANATOMY

Detailed explanation-1: -The parallels between allergy and the immune response to parasitic worms (helminths) have been noted for some time. There are however critical differences between the two conditions. More items •14-Feb-2014

Detailed explanation-2: -IgE is an antibody that your body makes. If you have allergies, you may have more IgE in your blood than normal. Allergies are a common, long-term condition that involves your immune system. Your immune system makes antibodies to fight off viruses, bacteria, and other things that can make you sick.

Detailed explanation-3: -If you have an allergy, your immune system overreacts to an allergen by producing antibodies called Immunoglobulin E (IgE). These antibodies travel to cells that release chemicals, causing an allergic reaction. This reaction usually causes symptoms in the nose, lungs, throat, or on the skin.

Detailed explanation-4: -Human IgE mAbs identify major antigens of parasitic worm infection-Journal of Allergy and Clinical Immunology.

Detailed explanation-5: -Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic reactions, and their powerful effector functions activated through binding to Fc receptors FcRI and FcRII/CD23.