ANATOMY

Detailed explanation-1: -Helper T cells are arguably the most important cells in adaptive immunity, as they are required for almost all adaptive immune responses. They not only help activate B cells to secrete antibodies and macrophages to destroy ingested microbes, but they also help activate cytotoxic T cells to kill infected target cells.

Detailed explanation-2: -T cells have dual specificity, so they recognize both self-major histocompatibility complex molecules (MHC I or MHC II) and peptide antigens displayed by those MHC molecules.

Detailed explanation-3: -T cells do not recognize free-floating or cell-bound antigens as they appear on the surface of the pathogen. They only recognize antigen on the surface of specialized cells called antigen-presenting cells.

Detailed explanation-4: -The T and B lymphocytes (T and B Cells) are involved in the acquired or antigen-specific immune response given that they are the only cells in the organism able to recognize and respond specifically to each antigenic epitope.

Detailed explanation-5: -T cells can detect the presence of an intracellular pathogen because infected cells display on their surface peptide fragments derived from the pathogen’s proteins. These foreign peptides are delivered to the cell surface by specialized host-cell glycoproteins.