ANATOMY

Detailed explanation-1: -Osteoblasts are specialised fibroblast-like cells of primitive mesenchymal origin called osteoprogenitor cell that originate from pluripotent mesenchymal stem cells of the bone marrow.

Detailed explanation-2: -Osteoblasts are the bone cells derived from osteochondral progenitor cells that form the bone through a process called ossification.

Detailed explanation-3: -They are found on the surface of the bone mineral next to the dissolving bone. OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus.

Detailed explanation-4: -Osteoblasts arise from the differentiation of mesenchymal cells committed to osteoprogenitors in the periosteum, via a process that requires sequential action of the transcription factors Runx2 and osterix [1].