ANATOMY

Detailed explanation-1: -Creatinine is a by-product of muscle metabolism in which creatine in the muscle is converted nonenzymatically to creatinine. Because the total body content of creatine is fairly constant, there is a continual production of creatinine and a continual excretion of it in the urine.

Detailed explanation-2: -Urea and creatinine are nitrogenous end products of metabolism. Urea is the primary metabolite derived from dietary protein and tissue protein turnover. Creatinine is the product of muscle creatine catabolism.

Detailed explanation-3: -creatinine clearance Creatinine is a chemical end product of creatine metabolism that is removed, or cleared, from blood plasma by glomeruli and is excreted in the urine.

Detailed explanation-4: -The reversible conversion of creatine to creatine phosphate by binding inorganic phosphate via the catalyst, creatine kinase. The reverse reaction produces ATP from ADP and the waste product, creatinine, which is excreted in urine.

Detailed explanation-5: -Creatine is an amino acid located mostly in your body’s muscles as well as in the brain. Most people get creatine through seafood and red meat-though at levels far below those found in synthetically made creatine supplements. The body’s liver, pancreas and kidneys also can make about 1 gram of creatine per day.