ANATOMY

Detailed explanation-1: -The lining of the uterus (endometrium) starts to thicken. One of the ovaries releases an egg. And then, if the egg isn’t fertilized or a fertilized egg doesn’t attach to the lining of the uterus (implant), the endometrium sheds from the uterus as a menstrual period.

Detailed explanation-2: -Menstruation is the shedding of the endometrium that occurs on a regular basis in females of reproductive age (Fig. 25.12). Plasmin in the endometrium tends to inhibit blood clotting. Normal, regular menstruation lasts for about 3–5 days.

Detailed explanation-3: -Normal menstrual bleeding depends on the sequential exposure of the estrogen-primed endometrium to estrogen and progesterone, followed by withdrawal of progesterone at the end of the menstrual cycle. Any endocrine irregularity that prevents these sequential events may potentially result in HMB.

Detailed explanation-4: -Endometrial hyperplasia thickens your uterine lining, causing heavy or abnormal bleeding. Atypical endometrial hyperplasia raises your risk of endometrial cancer and uterine cancer. The condition tends to occur during or after menopause. Progestin therapy can reduce your symptoms.