ANATOMY

GENERAL ANATOMY

URINARY SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Select all the substances that are secreted in the Proximal Convoluted Tubule
A
Glucose
B
Urea
C
Medication
D
Drugs
E
Ammonia
Explanation: 

Detailed explanation-1: -The PCT secretes: Organic acids and bases – e.g. bile salts, oxalate and catecholamines (waste products of metabolism) Hydrogen ions (H+) – important in maintaining acid/base balance in the body. H+ secretion allows reabsorption of bicarbonate via the use of the enzyme carbonic anhydrase (Fig 2).

Detailed explanation-2: -Ammonia is produced in the proximal tubule as a result of metabolism of glutamine (Gln) to NH4+ and HCO3−; ammonia is preferentially secreted into the luminal fluid as either NH4+ or NH3. Bicarbonate produced from ammoniagenesis is preferentially secreted across the basolateral membrane.

Detailed explanation-3: –Secretion is when substances in the efferent arteriole transfer into the proximal convoluted tubule.-Secretion occurs mainly in the proximal convoluted tubule.-H+, K+, urea, ammonia, uric acid.

Detailed explanation-4: -Potassium ions (K+) Hydrogen ions (H+) Ammonium ions (NH4+) Creatinine. Urea. Some hormones. Some drugs (e.g., penicillin) 17-Jan-2023

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