BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Description: Amides can be reduced to amines with a strong reducing agent like lithium aluminum hydride (LiAlH4).

Detailed explanation-2: -The Conversion of an amide by action of NaOH and Br2 to primary amine that has one carbon less than the starting amide is known as Hofmann-Bromamide reaction. Q. When primary amide is treated with an aqueous solution of KOH and bromine, it gives a primary amine.

Detailed explanation-3: -Amides on reduction with LiAlH4 form primary amines.

Detailed explanation-4: -Explanation: The Hofmann reaction is an organic reaction used to convert a primary amide to a primary amine. In the Hofmann reaction, an amide is treated with bromine and base (usually NaOH or KOH).

Detailed explanation-5: -When used alone, NaBH4 reduces aldehydes, ketones, acid chlorides, and in some cases esters, but not carboxylic acids, amides, nitriles, nitro compounds or halogenated organic molecules.