BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Hydrophobic amino acids have little or no polarity in their side chains. The lack of polarity means they have no way to interact with highly polar water molecules, making them water fearing.

Detailed explanation-2: -Hydrophobic amino acids have neutral non-polar side chains. Given the lack of polarity these groups have no means to interact with an aqueous biological environment.

Detailed explanation-3: -Hydrophilic amino acids are polar while hydrophobic amino acids are non-polar, this is the main difference between them.

Detailed explanation-4: -Our simulations show that all nonpolar amino acid side chains are hydrophobic ( > 90°), even though their peptide backbones are highly charged.