BIOMOLECULES AND ENZYMES

BIOLOGY

AMINO ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Reaction between aldehyde, NH4Cl and HCN to prepare
A
Curtius method
B
Darapsky synthesis
C
Strecker’s synthesis
D
Phthalimidomalonic ester synthesis
Explanation: 

Detailed explanation-1: -The Strecker amino acid synthesis, also known simply as the Strecker synthesis, is a method for the synthesis of amino acids by the reaction of an aldehyde with ammonia in the presence of potassium cyanide.

Detailed explanation-2: -The Strecker Synthesis is a way of making amino acids from aldehydes, via 1) formation of an imine, 2) addition of cyanide ion to give an alpha-amino nitrile, and then 3) hydrolysis of the nitrile to give a carboxylic acid.

Detailed explanation-3: -The Strecker synthesis is a two-step procedure for the synthesis of amino acids. It begins with the addition of cyanide ion to an imine, forming an alpha-amino nitrile. This is then hydrolyzed (e.g. with strong acid) to give an alpha-amino acid.

Detailed explanation-4: -The traditional Strecker synthesis yields a racemic mix-ture of L-and D-amino acids, but several procedures utilizing asymmetric catalysts have been developed.

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