BIOLOGY
AMINO ACIDS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Lysine
|
|
|
Arginine
|
|
|
Histidine
|
|
|
Serine
|
Detailed explanation-1: -Besides being the most alkaline amino acid, the arginine molecule contains a positively charged guanidine group, similar to guanidine hydrochloride, and has been used in many refolding systems to suppress protein aggregation.
Detailed explanation-2: -Lysine and arginine are the two positively charged amino acids in proteins that have high aqueous pKa’s ( 10.5 for Lys1 and 13.8 for Arg2) indicating a strong propensity to carry charge at physiological pH.
Detailed explanation-3: -Arginine, an essential amino acid, has a positively charged guanidino group.
Detailed explanation-4: -Substitutions: Arginine is a positively charged, polar amino acid.
Detailed explanation-5: -Positively and negatively charged side chains at cellular pH Panel 1: The 3 positively charged amino acids are shown. These are: histidine (His, H), lysine (Lys, K), and arginine (Arg, R).