BIOMOLECULES AND ENZYMES

BIOLOGY

AMINO ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the amino acid which contains 2 carboxylic groups?
A
Alanine (A)-Ala
B
Serine (S)-Ser
C
Aspartate (D)-Asp
D
Tyrosine (Y)-Tyr
Explanation: 

Detailed explanation-1: -The IUPAC name is 2-aminobuanedioic acid. ASP is chiral and exists in two enantiomeric forms, l-aspartate and d-aspartate where l-aspartate is the form used in protein biosynthesis (proteinogenic) and neurotransmission.

Detailed explanation-2: -Glutamic acid has two carboxyl groups.

Detailed explanation-3: -Its -amino group is in the protonated –NH+3 form under physiological conditions, while its -carboxylic acid group is deprotonated −COO− under physiological conditions. Aspartic acid has an acidic side chain (CH2COOH) which reacts with other amino acids, enzymes and proteins in the body.

Detailed explanation-4: -The isoelectric point of aspartic acid is 2.77 because of two carboxyl groups in the molecule. The pKa value of carboxyl group bonded on alpha carbon is 1.88, for-COOH group at the side chain is 3.65 and for amino group is 9.60.

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