BIOMOLECULES AND ENZYMES

BIOLOGY

AMINO ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following statements related to the Ramachandran plot is not true?
A
Almost all peptide bonds in proteins are cis.
B
The restriction of psi and phi angles limits structures accessible to unfolded form of proteins.
C
A configuration that has
D
Three quarters of possible phi and psi values are excluded by their steric clashes.
Explanation: 

Detailed explanation-1: -Peptides that are unstructured will have all the backbone dihedral angles in the. disallowed regions.

Detailed explanation-2: -Explanation: Glycine and proline are an exception to the Ramachandran plot.

Detailed explanation-3: -The Ramachandran plot shows the statistical distribution of the combinations of the backbone dihedral angles and . In theory, the allowed regions of the Ramachandran plot show which values of the Phi/Psi angles are possible for an amino acid, X, in a ala-X-ala tripeptide (Ramachandran et al., 1963).

Detailed explanation-4: -Updated On: 27-06-2022 Due to resonance, C-N bond length in proteins is smaller than usual bond length of C−N bond. Therefore, option (a) is incorrect.

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