BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The denaturation of protein changes the structural configurations of the protein especially in its three-dimensional shape. As the denaturation does not affect the peptide bonds, the primary structure of the proteins is not affected.

Detailed explanation-2: -A weak bond, known as a hydrogen bond, forms between a hydrogen atom and an oxygen atom in the amino acids. This gives the protein its shape. What is denaturing and how does it happen? A protein becomes denatured when its normal shape gets deformed because some of the hydrogen bonds are broken.

Detailed explanation-3: -During the denaturation of proteins, the secondary and tertiary structures get destroyed and only the primary structure is retained. Covalent bonds are broken and interaction between amino-acid chains gets disrupted. This results in the loss of biological activity of the proteins.

Detailed explanation-4: -Denaturation breaks the covalent bonds that hold the protein in its three-dimensional shape. Without the proper shape, the protein cannot function. Denaturation destroys the primary structure of the protein, and the protein breaks down to monomers.

Detailed explanation-5: -If the protein is subject to changes in temperature, pH, or exposure to chemicals, the protein structure may change, losing its shape without losing its primary sequence in what is known as denaturation.