BIOMOLECULES AND ENZYMES

BIOLOGY

ENZYMES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A change in pH can change the shape of a protein. How might a change in pH affect the function of an enzyme?
A
A new enzyme may be required to speed up the reaction.
B
The enzyme may no longer be able to function for the substrate as a catalyst.
C
The enzyme and substrate may no longer fit together so the enzyme cannot speed up the reaction.
D
All the other answers are correct.
Explanation: 

Detailed explanation-1: -The change of pH will lead to the ionization of amino acids atoms and molecules, change the shape and structure of proteins, thus damaging the function of proteins. Enzymes are also proteins, which are also affected by changes in pH.

Detailed explanation-2: -Changing the Shape of a Protein If the protein is subject to changes in temperature, pH, or exposure to chemicals, the internal interactions between the protein’s amino acids can be altered, which in turn may alter the shape of the protein.

Detailed explanation-3: -Changing the pH will affect the charges on the amino acid molecules. Amino acids that attracted each other may no longer be. Again, the shape of the enzyme, along with its active site, will change. Extremes of pH also denature enzymes.

Detailed explanation-4: -Denaturation and protein folding If the temperature or pH of a protein’s environment is changed, or if it is exposed to chemicals, these interactions may be disrupted, causing the protein to lose its three-dimensional structure and turn back into an unstructured string of amino acids.

Detailed explanation-5: -Changing the pH disrupts the hydrogen bonds, and this changes the shape of the protein.

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