BIOMOLECULES AND ENZYMES

BIOLOGY

ENZYMES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
An enzyme works optimally at a pH between 2 and 4. Which best explains what will happen to this enzyme at a pH of 12?
A
It will lose its original shape and work on new substrates.
B
It will work on a different substrate than at a pH range of 2-4.
C
It will lose its original shape and not work on any substrate at all.
D
It will work on the same substrate as it did at a pH range of 2-4, butit will not work as well.
Explanation: 

Detailed explanation-1: -An enzyme works optimally at a pH between 2 and 4. Which best explains what will happen to this enzyme at a pH of 12? It will lose its original shape and work on new substrates.

Detailed explanation-2: -Description. Enzyme activity is at its maximum value at the optimum pH. As the pH value is increased above or decreased below the optimum pH the enzyme activity decreases.

Detailed explanation-3: -pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-4: -Changing the pH will affect the charges on the amino acid molecules. Amino acids that attracted each other may no longer be. Again, the shape of the enzyme, along with its active site, will change. Extremes of pH also denature enzymes.

Detailed explanation-5: -For example, the enzyme pepsin is found in the stomach. The stomach produces hydrochloric acid, which makes the contents of the stomach very acidic. The enzyme pepsin has evolved to work best at a pH of 2, which is the pH of the stomach; the optimal pH for pepsin is 2.

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