BIOMOLECULES AND ENZYMES

Detailed explanation-1: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-2: -Several factors affect the rate at which enzymatic reactions proceed-temperature, pH, enzyme concentration, substrate concentration, and the presence of any inhibitors or activators.

Detailed explanation-3: -The proteins in enzymes are usually globular. The intra-and intermolecular bonds that hold proteins in their secondary and tertiary structures are disrupted by changes in temperature and pH. This affects shapes and so the catalytic activity of an enzyme is pH and temperature sensitive.